Founded in 1961, the Society of Toxicology (SOT) is a professional and scholarly organization of scientists from academic institutions, government, and industry representing the great variety of scientists who practice toxicology in the US and abroad. The Society’s mission is to create a safer and healthier world by advancing the science and increasing the impact of toxicology.
Toxicology Learning Framework
Society Learning Goals | Articles | Sample Learning Objectives |
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How is the use of model organisms fundamental to toxicology? |
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How have toxins evolved? |
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How have xenobiotic defense mechanism evolved? |
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How do toxicants exert selection pressures? |
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How does carcinogenesis occur in response to genotoxic and nongenotoxic carcinogens? |
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What effects can the environment have on gene expression? |
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How do biomarkers indicate exposure to toxicants? |
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What differences occur in how individuals or populations are affected by exposure to different doses of a toxicant? |
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How do predisposing factors such as variations in health, gender, and age affect the response of a population to a toxicant? |
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What is the connection between toxicology and epidemiology? |
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Why are certain populations at greater risk from exposure to toxicants? |
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How are organisms living in the natural environment affected by natural and anthropogenic toxicants? |
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How is the science of toxicology applied to government regulations to ensure the protection of individuals and the environment? |
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How does poison management protect human health through a knowledge of poisons and their antidotes? |
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How have historical incidents impacted the development of the regulatory laws concerning toxicology? |
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How do cells respond to exposure to toxicants? |
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How are organs affected by exposure to toxicants? |
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How are body systems affected by exposure to toxicants? |
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How do toxicants affect an organism’s development and reproduction? |
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How do toxicants move through the environment to affect ecosystems? |
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How do toxicants affect homeostasis for exposed organisms? |
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How does the concept of dose-response relate to toxicology? |
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How do concepts of administration, distribution, metabolism, and elimination(ADME) help characterize the mechanism of action of toxicants? |
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How can ADME be quantified using toxicodynamics and toxicokinetics (TDTK)? |
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What is the relationship between toxicology and pharmacology? |
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How does oxidative stress contribute to toxicology? |
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What effects can toxicants have on energy metabolism? |
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