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Signaling

Developmental Biology Learning Framework

Society Learning Goals Articles Sample Learning Objectives
Signaling
How does the intracellular communication regulate gene transcription, cell polarity, shape and fate?
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  • Compare the roles of different transmembrane signaling pathways in development.
How does differential gene expression mediate progressive acquisition of cell fate?
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  • Explain how Hox genes control patterning along the anterior-posterior axis and in many developing organs.
  • Explain how proliferative signals moderate transcription factor activity and subsequently lead to lockdown of fate.
How do induction mechanisms and pathways influence cell fate?
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  • Compare the roles of different transmembrane signaling pathways in development.
How do mechanical constraints and dynamics influence cell behavior, tissue and organ formation?
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  • Predict changes (or not) in development taken place in microgravity environment.

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