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Air Quality Data Mining: Mining the US EPA AirData website for student-led evaluation of air quality issuesLearning ObjectivesStudents will be able to:
- Describe various parameters of air quality that can negatively impact human health, list priority air pollutants, and interpret the EPA Air Quality Index as it relates to human health.
- Identify an air quality problem that varies on spatial and/or temporal scales that can be addressed using publicly available U.S. EPA air data.
- Collect appropriate U.S. EPA Airdata information needed to answer that/those questions, using the U.S. EPA Airdata website data mining tools.
- Analyze the data as needed to address or answer their question(s).
- Interpret data and draw conclusions regarding air quality levels and/or impacts on human and public health.
- Communicate results in the form of a scientific paper.
Out of Your Seat and on Your Feet! An adaptable course-based research project in plant ecology for advanced studentsLearning ObjectivesStudents will:
- Articulate testable hypotheses. (Lab 8, final presentation/paper, in-class exercises)
- Analyze data to determine the level of support for articulated hypotheses. (Labs 4-7, final presentation/paper)
- Identify multiple species of plants in the field quickly and accurately. (Labs 2-3, field trip)
- Measure environmental variables and sample vegetation in the field. (Labs 2-3, field trip)
- Analyze soil samples using a variety of low-tech lab techniques. (Open labs after field trip)
- Use multiple statistical techniques to analyze data for patterns. (Labs 4-8, final presentation/paper)
- Interpret statistical analyses to distinguish between strong and weak interactions in a biological system. (Labs 4-7, final presentation/paper)
- Develop and present a conference-style presentation in a public forum. (Lab 8, final presentation/paper)
- Write a publication-ready research paper communicating findings and displaying data. (Lab 8, final presentation/paper)
Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle...Learning Objectives
- Students will define a Poisson distribution.
- Students will generate a data set on the probability of a T cell being infected with a virus(es).
- Students will predict the likelihood of one observing the mean value of viruses occurring.
- Students will evaluate the outcomes of a random process.
- Students will hypothesize whether a process is Poissonian and design a test for that hypothesis.
- Students will collect data and create a histogram from their data.
Meiosis: A Play in Three Acts, Starring DNA SequenceLearning Objectives
- Students will be able to identify sister chromatids and homologous chromosomes at different stages of meiosis.
- Students will be able to identify haploid and diploid cells, whether or not the chromosomes are replicated.
- Students will be able to explain why homologous chromosomes must pair during meiosis.
- Students will be able to relate DNA sequence similarity to chromosomal structures.
- Students will be able to identify crossing over as the key to proper pairing of homologous chromosomes during meiosis.
- Students will be able to predict the outcomes of meiosis for a particular individual or cell.
What do Bone and Silly Putty® have in Common?: A Lesson on Bone ViscoelasticityLearning Objectives
- Students will be able to explain how the anatomical structure of long bones relates to their function.
- Students will be able to define viscoelasticity, hysteresis, anisotropy, stiffness, strength, ductility, and toughness.
- Students will be able to identify the elastic and plastic regions of a stress-strain curve. They will be able to correlate each phase of the stress-strain curve with physical changes to bone.
- Students will be able to predict how a bone would respond to changes in the magnitude of an applied force, and to variations in the speed or angle at which a force is applied.
- Students will be able to determine the reason(s) why bone injuries occur more frequently during athletic events than during normal everyday use.
A Close-Up Look at PCRLearning ObjectivesAt the end of this lesson students will be able to...
- Describe the role of a primer in PCR
- Predict sequence and length of PCR product based on primer sequences
- Recognize that primers are incorporated into the final PCR products and explain why
- Identify covalent and hydrogen bonds formed and broken during PCR
- Predict the structure of PCR products after each cycle of the reaction
- Explain why amplification proceeds exponentially
An undergraduate bioinformatics curriculum that teaches eukaryotic gene structureLearning ObjectivesModule 1
- Demonstrate basic skills in using the UCSC Genome Browser to navigate to a genomic region and to control the display settings for different evidence tracks.
- Explain the relationships among DNA, pre-mRNA, mRNA, and protein.
- Describe how a primary transcript (pre-mRNA) can be synthesized using a DNA molecule as the template.
- Explain the importance of the 5' and 3' regions of the gene for initiation and termination of transcription by RNA polymerase II.
- Identify the beginning and the end of a transcript using the capabilities of the genome browser.
- Explain how the primary transcript generated by RNA polymerase II is processed to become a mature mRNA, using the sequence signals identified in Module 2.
- Use the genome browser to analyze the relationships among:
- 5' capping
- 3' polyadenylation
- Identify splice donor and acceptor sites that are best supported by RNA-Seq data and TopHat splice junction predictions.
- Utilize the canonical splice donor and splice acceptor sequences to identify intron-exon boundaries.
- Determine the codons for specific amino acids and identify reading frames by examining the Base Position track in the genome browser.
- Assemble exons to maintain the open reading frame (ORF) for a given gene.
- Define the phases of the splice donor and acceptor sites and describe how they impact the maintenance of the ORF.
- Identify the start and stop codons of an assembled ORF.
- Demonstrate how alternative splicing of a gene can lead to different mRNAs.
- Show how alternative splicing can lead to the production of different polypeptides and result in drastic changes in phenotype.
Authentic Ecological Inquiries Using BearCam ArchivesLearning ObjectivesStudents will be able to:
- conduct an authentic ecological inquiry including
- generate a testable hypothesis based on observations,
- design investigation with appropriate sampling selection and variables,
- collect and analyze data following the design, and
- interpret results and draw conclusions based on the evidence.
- write a research report with appropriate structure and style.
- evaluate the quality of inquiry reports using a rubric.
- conduct peer review to evaluate and provide feedback to others' work.
- revise the inquiry report based on peer feedback and self-assessment.
- conduct an authentic ecological inquiry including
Using the Cell Engineer/Detective Approach to Explore Cell Structure and FunctionLearning ObjectivesStudents will be able to:
- Identify the major cell organelles
- List the major functions of the organelles
- Predict how changes in organelle/cell structure could alter cellular function
- Explain how overall cellular function is dependent upon organelles/cell structure
- Relate cell structure to everyday contexts