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  • blind cave fish
  • The MAP Kinase signal transduction pathway

    Cell Signaling Pathways - a Case Study Approach

    Learning Objectives
    • Use knowledge of positive and negative regulation of signaling pathways to predict the outcome of genetic modifications or pharmaceutical manipulation.
    • From phenotypic data, predict whether a mutation is in a coding or a regulatory region of a gene involved in signaling.
    • Use data, combined with knowledge of pathways, to make reasonable predictions about the genetic basis of altered signaling pathways.
    • Interpret and use pathway diagrams.
    • Synthesize information by applying prior knowledge on gene expression when considering congenital syndromes.
  • A pair of homologous chromosomes.

    Meiosis: A Play in Three Acts, Starring DNA Sequence

    Learning Objectives
    • Students will be able to identify sister chromatids and homologous chromosomes at different stages of meiosis.
    • Students will be able to identify haploid and diploid cells, whether or not the chromosomes are replicated.
    • Students will be able to explain why homologous chromosomes must pair during meiosis.
    • Students will be able to relate DNA sequence similarity to chromosomal structures.
    • Students will be able to identify crossing over as the key to proper pairing of homologous chromosomes during meiosis.
    • Students will be able to predict the outcomes of meiosis for a particular individual or cell.
  • Confocal microscope image of a mouse egg that is arrested at metaphase of meiosis II. Green, tubulin staining of meiotic spindle; red, actin staining of egg membrane; blue, DNA. This image was obtained on a Zeiss 510 Meta confocal microscope in the Department of Genetics at Rutgers University

    Sex-specific differences in Meiosis: Real-world applications

    Learning Objectives
    After completion of the lesson students will be able to:
    1. Describe the differences between female and male meiosis.
    2. Interpret graphical data to make decisions relevant to medical practices.
    3. Develop a hypothesis that explains the difference in incidence of aneuploidy in gametes between males and females.
  • An active-learning lesson that targets student understanding of population growth in ecology

    Learning Objectives
    Students will be able to:
    • Calculate and compare population density and abundance.
    • Identify whether a growth curve describes exponential, linear, and/or logistic growth.
    • Describe and calculate a population's growth rate using linear, exponential, and logistic models.
    • Explain the influence of carrying capacity and population density on growth rate.