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- (-) Remove Introductory Biology filter Introductory Biology
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Bloom's Cognitive Level
Vision and Change Core Competencies
Vision and Change Core Concepts
Key Scientific Process Skills
Principles of How People Learn
Dynamic Daphnia: An inquiry-based research experience in ecology that teaches the scientific process to first-year...Learning ObjectivesStudents will be able to:
- Construct written predictions about 1 factor experiments.
- Interpret simple (2 variables) figures.
- Construct simple (2 variables) figures from data.
- Design simple 1 factor experiments with appropriate controls.
- Demonstrate proper use of standard laboratory items, including a two-stop pipette, stereomicroscope, and laboratory notebook.
- Calculate means and standard deviations.
- Given some scaffolding (instructions), select the correct statistical test for a data set, be able to run a t-test, ANOVA, chi-squared test, and linear regression in Microsoft Excel, and be able to correctly interpret their results.
- Construct and present a scientific poster.
Discovery Poster ProjectLearning ObjectivesStudents will be able to:
- identify and learn about a scientific research discovery of interest to them using popular press articles and the primary literature
- find a group on campus doing research that aligns with their interests and communicate with the faculty leader of that group
- create and present a poster that synthesizes their knowledge of the research beyond the discovery
Discovering Prokaryotic Gene Regulation with Simulations of the trp OperonLearning ObjectivesStudents will be able to:
- Perturb and interpret simulations of the trp operon.
- Define how simulation results relate to cellular events.
- Describe the biological role of the trp operon.
- Describe cellular mechanisms regulating the trp operon.
- Explain mechanistically how changes in the extracellular environment affect the trp operon.
- Define the impact of mutations on trp operon expression and regulation.
Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant GerminationLearning ObjectivesStudents will be able to:
- identify when germination occurs.
- score germination in the presence and absence of GA to construct graphs of collated class data of wild-type and mutant specimens.
- identify the genotype of an unknown sample based on the analysis of their graphical data.
- organize data and perform quantitative data analysis.
- explain the importance of GA for plant germination.
- connect the inheritance of a mutation with the observed phenotype.
Meiosis: A Play in Three Acts, Starring DNA SequenceLearning Objectives
- Students will be able to identify sister chromatids and homologous chromosomes at different stages of meiosis.
- Students will be able to identify haploid and diploid cells, whether or not the chromosomes are replicated.
- Students will be able to explain why homologous chromosomes must pair during meiosis.
- Students will be able to relate DNA sequence similarity to chromosomal structures.
- Students will be able to identify crossing over as the key to proper pairing of homologous chromosomes during meiosis.
- Students will be able to predict the outcomes of meiosis for a particular individual or cell.
A clicker-based case study that untangles student thinking about the processes in the central dogmaLearning ObjectivesStudents will be able to:
- explain the differences between silent (no change in the resulting amino acid sequence), missense (a change in the amino acid sequence), and nonsense (a change resulting in a premature stop codon) mutations.
- differentiate between how information is encoded during DNA replication, transcription, and translation.
- evaluate how different types of mutations (silent, missense, and nonsense) and the location of those mutations (intron, exon, and promoter) differentially affect the processes in the central dogma.
- predict the molecular (DNA size, mRNA length, mRNA abundance, and protein length) and/or phenotypic consequences of mutations.
Antibiotic Resistance Genes Detection in Environmental SamplesLearning ObjectivesAfter completing this laboratory series, students will be able to:
- apply the scientific method in formulating a hypothesis, designing a controlled experiment using appropriate molecular biology techniques, and analyzing experimental results;
- conduct a molecular biology experiment and explain the principles behind methodologies, such as accurate use of micropipettes, PCR (polymerase chain reaction), and gel electrophoresis;
- determine the presence of antibiotic-resistance genes in environmental samples by analyzing PCR products using gel electrophoresis;
- explain mechanisms of microbial antibiotic resistance;
- contribute data to the Antibiotic Resistance Genes Network;
- define and apply key concepts of antibiotic resistance and gene identification via PCR fragment size.
Follow the Sulfur: Using Yeast Mutants to Study a Metabolic PathwayLearning ObjectivesAt the end of this lesson, students will be able to:
- use spot plating techniques to compare the growth of yeast strains on solid culture media.
- predict the ability of specific met deletion strains to grow on media containing various sulfur sources.
- predict how mutations in specific genes will affect the concentrations of metabolites in the pathways involved in methionine biosynthesis.
A first lesson in mathematical modeling for biologists: RocsLearning Objectives
- Systematically develop a functioning, discrete, single-species model of an exponentially-growing or -declining population.
- Use the model to recommend appropriate action for population management.
- Communicate model output and recommendations to non-expert audiences.
- Generate a collaborative work product that most individuals could not generate on their own, given time and resource constraints.
Air Quality Data Mining: Mining the US EPA AirData website for student-led evaluation of air quality issuesLearning ObjectivesStudents will be able to:
- Describe various parameters of air quality that can negatively impact human health, list priority air pollutants, and interpret the EPA Air Quality Index as it relates to human health.
- Identify an air quality problem that varies on spatial and/or temporal scales that can be addressed using publicly available U.S. EPA air data.
- Collect appropriate U.S. EPA Airdata information needed to answer that/those questions, using the U.S. EPA Airdata website data mining tools.
- Analyze the data as needed to address or answer their question(s).
- Interpret data and draw conclusions regarding air quality levels and/or impacts on human and public health.
- Communicate results in the form of a scientific paper.
Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying...Learning Objectives
- Describe how cells can produce proteins at the right time and correct amount.
- Diagram how a repressor works to reduce transcription.
- Diagram how an activator works to increase transcription.
- Identify a new promoter from literature and design a method to clone it and test its function.
- Successfully and safely manipulate DNA and Escherichia coli for ligation and transformation experiments.
- Design an experiment to verify a new promoter has been cloned into a destination vector.
- Design an experiment to measure the strength of a promoter.
- Analyze data showing reporter protein produced and use the data to assess promoter strength.
- Define type IIs restriction enzymes.
- Distinguish between type II and type IIs restriction enzymes.
- Explain how Golden Gate Assembly (GGA) works.
- Measure the relative strength of a promoter compared to a standard promoter.
Using Pathway Maps to Link Concepts, Peer Review, Primary Literature Searches and Data Assessment in Large Enrollment...Learning Objectives
- Define basic concepts and terminology of Ecosystem Ecology
- Link biological processes that affect each other
- Evaluate whether the link causes a positive, negative, or neutral effect
- Find primary literature
- Identify data that correctly supports or refutes an hypothesis
Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics...Learning ObjectivesStudents successfully completing this lesson will:
- Practice navigating an online bioinformatics resource and identify evidence relevant to solving investigation questions
- Contrast the array of genes expected on homologous autosomal chromosomes pairs with the array of genes expected on sex chromosome pairs
- Use bioinformatics evidence to defend the definition of homologous chromosomes
- Define chromosomal sex and defend the definition using experimental data
- Investigate the genetic basis of human chromosomal sex determination
- Identify at least two genetic mutations can lead to sex reversal
You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”Learning ObjectivesStudents will be able to:
- Explain both beneficial and detrimental roles of microbes in human health.
- Compare and contrast DNA replication as it occurs inside a cell versus in a test tube
- Identify an unknown sequence of DNA by performing a BLAST search
- Navigate sources of scientific information to assess the accuracy of their experimental techniques