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Discovering Prokaryotic Gene Regulation by Building and Investigating a Computational Model of the lac OperonLearning ObjectivesStudents will be able to:
- model how the components of the lac operon contribute to gene regulation and expression.
- generate and test predictions using computational modeling and simulations.
- interpret and record graphs displaying simulation results.
- relate simulation results to cellular events.
- describe how changes in environmental glucose and lactose levels impact regulation of the lac operon.
- predict, test, and explain how mutations in specific elements in the lac operon affect their protein product and other elements within the operon.
Discovering Prokaryotic Gene Regulation with Simulations of the trp OperonLearning ObjectivesStudents will be able to:
- Perturb and interpret simulations of the trp operon.
- Define how simulation results relate to cellular events.
- Describe the biological role of the trp operon.
- Describe cellular mechanisms regulating the trp operon.
- Explain mechanistically how changes in the extracellular environment affect the trp operon.
- Define the impact of mutations on trp operon expression and regulation.