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Developmental Biology

  • Student-generated targeting construct from the construct ribbon parts

    Make It Stick: Teaching Gene Targeting with Ribbons and Fasteners

    Learning Objectives
    • Students will be able to design targeting constructs.
    • Students will be able to predict changes to the gene locus after homologous recombination.
    • Students will be able to design experiments to answer a biological question (e.g., "Design an experiment to test if the expression of gene X is necessary for limb development").
  • Training future faculty map

    Training future faculty in 30 minutes a week: A modular framework to provide just-in-time professional development to...

    Learning Objectives
    TAs will be able to:
    • design small classroom activities
    • design fair quiz and exam questions
    • use rubrics to grade assignments fairly and in a timely manner
    • offer constructive, actionable feedback on student written work
    • compare and contrast context-specific strategies for dealing with student problems
    • compare and contrast context-specific time management strategies
    • discuss the importance of diversity, evaluate their own implicit biases, and discuss how these could impact their teaching
    • compare and contrast different methods of summarizing teaching experience on job application materials
    • evaluate their teaching in a reflective manner to develop future teaching goals
  • The MAP Kinase signal transduction pathway

    Cell Signaling Pathways - a Case Study Approach

    Learning Objectives
    • Use knowledge of positive and negative regulation of signaling pathways to predict the outcome of genetic modifications or pharmaceutical manipulation.
    • From phenotypic data, predict whether a mutation is in a coding or a regulatory region of a gene involved in signaling.
    • Use data, combined with knowledge of pathways, to make reasonable predictions about the genetic basis of altered signaling pathways.
    • Interpret and use pathway diagrams.
    • Synthesize information by applying prior knowledge on gene expression when considering congenital syndromes.
  • Aldh1a2 expression in Stage 33 Xenopus laevis embryo: In this lab exercise, students visualize differential gene expression in Xenopus embryos using in situ hybridization.

    Differential Gene Expression during Xenopus laevis Development

    Learning Objectives
    Students will be able to:
    • identify different stages of Xenopus development
    • contrast the strengths and limitations of the Xenopus model organism
    • explain the process and purpose of in situ hybridization
    • compare gene expression patterns from different germ layers or organ domains
    • compare gene expression patterns from different developmental stages
  • Arabidopsis Seedling

    Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination

    Learning Objectives
    Students will be able to:
    • identify when germination occurs.
    • score germination in the presence and absence of GA to construct graphs of collated class data of wild-type and mutant specimens.
    • identify the genotype of an unknown sample based on the analysis of their graphical data.
    • organize data and perform quantitative data analysis.
    • explain the importance of GA for plant germination.
    • connect the inheritance of a mutation with the observed phenotype.