Skip to main content

You are here

Filters

Search found 7 items

Cell Biology

  • Arabidopsis Seedling

    Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination

    Learning Objectives
    Students will be able to:
    • identify when germination occurs.
    • score germination in the presence and absence of GA to construct graphs of collated class data of wild-type and mutant specimens.
    • identify the genotype of an unknown sample based on the analysis of their graphical data.
    • organize data and perform quantitative data analysis.
    • explain the importance of GA for plant germination.
    • connect the inheritance of a mutation with the observed phenotype.
  • Science press release cartoon.  Cartoon of a newspaper with the headline “Extra Extra! Cell Biology Makes Headlines!”

    Teaching students to read, interpret, and write about scientific research: A press release assignment in a large, lower...

    Learning Objectives
    Students will:
    • interpret the main conclusions and their supporting evidence in a primary research article.
    • concisely communicate the significance of scientific findings to an educated nonspecialist audience.
    • identify the components of a primary research article and the components of the "inverted pyramid" press release structure.
    • identify the central figure in a primary research paper and describe its key finding.
    • demonstrate an understanding of intellectual property by giving appropriate credit to other people's original work.
  • Structure of protein ADA2

    Understanding Protein Domains: A Modular Approach

    Learning Objectives
    • Students will be able to compare protein sequences and identify conserved regions and putative domains.
    • Students will be able to obtain, examine, and compare structural models of protein domains.
    • Students will be able to interpret data on protein interactions (in vitro pull-down and in vitro and in vivo functional assays)
    • Students will be able to propose experiments to test protein interactions.
  • Abelson kinase signaling network. The image shows many connections between genes and illustrates that signaling molecules and pathways function within networks. It emphasizes the indispensability of computational tools in understanding the molecular functioning of cells. The image was generated with Cytoscape from publicly accessible protein-protein interactions databases.

    Investigating Cell Signaling with Gene Expression Datasets

    Learning Objectives
    Students will be able to:
    • Explain the hierarchical organization of signal transduction pathways.
    • Explain the role of enzymes in signal propagation and amplification.
    • Recognize the centrality of signaling pathways in cellular processes, such as metabolism, cell division, or cell motility.
    • Rationalize the etiologic basis of disease in terms of deranged signaling pathways.
    • Use software to analyze and interpret gene expression data.
    • Use an appropriate statistical method for hypotheses testing.
    • Produce reports that are written in scientific style.
  • Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course

    Learning Objectives
    At the end of the activity, students will be able to:
    • Analyze data from a retrospective clinical study uncovering genetic alterations in colorectal cancer.
    • Draw conclusions about human tumorigenesis using data from a retrospective clinical study.
    • Present scientific data in an appropriate and accurate way.
    • Discuss why modeling is an important practice of science.
    • Create a simple model of the genetic changes associated with a particular human cancer.
  • The MAP Kinase signal transduction pathway

    Cell Signaling Pathways - a Case Study Approach

    Learning Objectives
    • Use knowledge of positive and negative regulation of signaling pathways to predict the outcome of genetic modifications or pharmaceutical manipulation.
    • From phenotypic data, predict whether a mutation is in a coding or a regulatory region of a gene involved in signaling.
    • Use data, combined with knowledge of pathways, to make reasonable predictions about the genetic basis of altered signaling pathways.
    • Interpret and use pathway diagrams.
    • Synthesize information by applying prior knowledge on gene expression when considering congenital syndromes.
  • A pair of homologous chromosomes.

    Meiosis: A Play in Three Acts, Starring DNA Sequence

    Learning Objectives
    • Students will be able to identify sister chromatids and homologous chromosomes at different stages of meiosis.
    • Students will be able to identify haploid and diploid cells, whether or not the chromosomes are replicated.
    • Students will be able to explain why homologous chromosomes must pair during meiosis.
    • Students will be able to relate DNA sequence similarity to chromosomal structures.
    • Students will be able to identify crossing over as the key to proper pairing of homologous chromosomes during meiosis.
    • Students will be able to predict the outcomes of meiosis for a particular individual or cell.