Skip to main content

You are here

Filters

Search found 1 item

Biochemistry And Molecular Biology

  • This is the question when working with pH and pKa. This is original artwork by the author and no copyright is violated.

    Taking the Hassle out of Hasselbalch

    Learning Objectives
    Students will be able to:
    1. Characterize an aqueous environment as acidic or basic.
    2. Explain that pKa is a measure of how easy it is to remove a proton from a molecule.
    3. Predict ionization state of a molecule at a particular pH based on its pKa (qualitative use of the Henderson-Hasselbalch equation).
    4. Calculate the ratio of protonated/unprotonated forms of ionizable groups depending on chemical characteristics and /or environment pH (quantitative use of the Henderson-Hasselbalch equation).
    5. Apply this knowledge in a medical context.