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Gene Networks

Developmental Biology Learning Framework

Society Learning Goals Articles Sample Learning Objectives
Gene Networks
How does the control of gene regulation contribute to development?
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  • Predict different mechanisms that could be responsible for control of gene expression in development.
How do genomic and epigenetic changes modify the transcriptome of a cell?
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  • Explain roles heterochromatin serves during development (e.g. Methylation on MyoD’s ability to induce the myogenic program in a non-muscle cell).
  • What changes in chromatin prime a cell to respond to later signals?
How do feedback loops affect multiple levels of gene regulation?
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  • Describe experiments that test the idea that floral homeotic gene (or ABCE gene) expression ensures the development of floral organs in the correct number, type, and precise spatial arrangement.
How do differences in regulation of gene expression explain the different cell types?
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  • Propose a mechanism that may explain differences in cell type behavior as a result of different gene expression (e.g. In time or site).
How do differences in regulation of gene expression explain the formation of atypical cells, tissue, organs and structures?
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  • Provide examples of how overexpression of an mRNA affects: 1) axis formation; 2) cell differentiation; 3) tissue formation.

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