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Developmental Biology Learning Framework

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Gene Networks
How does the control of gene regulation contribute to development?	Contribute an article in this area.	show Predict different mechanisms that could be responsible for control of gene expression in development.
How do genomic and epigenetic changes modify the transcriptome of a cell?	A clicker-based case study that untangles student thinking about the processes in the central dogma	show Explain roles heterochromatin serves during development (e.g. Methylation on MyoD’s ability to induce the myogenic program in a non-muscle cell). What changes in chromatin prime a cell to respond to later signals?
How do feedback loops affect multiple levels of gene regulation?	Contribute an article in this area.	show Describe experiments that test the idea that floral homeotic gene (or ABCE gene) expression ensures the development of floral organs in the correct number, type, and precise spatial arrangement.
How do differences in regulation of gene expression explain the different cell types?	Investigating Gene Expression and Cell Specialization in Axolotl Embryos	show Propose a mechanism that may explain differences in cell type behavior as a result of different gene expression (e.g. In time or site).
How do differences in regulation of gene expression explain the formation of atypical cells, tissue, organs and structures?	Make It Stick: Teaching Gene Targeting with Ribbons and Fasteners	show Provide examples of how overexpression of an mRNA affects: 1) axis formation; 2) cell differentiation; 3) tissue formation.