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Experimental Approaches

Developmental Biology Learning Framework

Society Learning Goals Articles Sample Learning Objectives
Experimental Approaches
How do the methods and tools of developmental biology help us understand cause and effect relationships during embryogenesis? (correlation, gain of function and loss of function; molecular, cellular, tissue, organ)
  • Design an experiment to detect the identification and/or position of potential stem cells in a tissue that is known to renew itself (e.g. skin, intestinal epithelium). Include positive and negative controls (one of each) that you would perform and the purpose of each control.
  • Given an article about the use of specific reagents in a developing organism and resulting phenotype(s), propose and explain potential mechanisms (e.g. induction, gene knockout) and give other examples using the same mechanisms.
How do different organisms help us understand development? And what are their strengths and limitations?
  • Explain how studying other species inform us about differences in developmental process that led some organisms to preserve certain characteristics and others to lose them?
  • Design a fate mapping experiment in an organism after learning how it is done in a different one.


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