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Biochemistry and Molecular Biology Learning Framework

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Discovery requires objective measurement, quantitative analysis and clear communication
What is the scientific process?	CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter Using CRISPR-Cas9 to teach the fundamentals of molecular biology and experimental design	show Accurately prepare and use reagents and perform the required experiments. When presented with an observation, develop a testable and falsifiable hypothesis. When provided with a hypothesis, identify the appropriate experimental observations and controllable variables. Determine averages and standard deviations to relate the significance of experimentally obtained data. Use equations and models to predict outcomes of experiments. Use appropriate equations to analyze experimental data and obtain parameters.
What skills are needed to access, comprehend and communicate science?	A virtual laboratory on cell division using a publicly-available image database Investigating Cell Signaling with Gene Expression Datasets Using CRISPR-Cas9 to teach the fundamentals of molecular biology and experimental design	show Identify, locate and use the primary literature. Use databases and bioinformatics tools. When provided with appropriate background information, identify consistencies and inconsistencies. Explain the big picture aspects of current challenges in the molecular life sciences. Use visual and verbal tools to explain concepts and data. Translate science into everyday examples.
What constitutes a scientific community of practice?	CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students Using CRISPR-Cas9 to teach the fundamentals of molecular biology and experimental design	show Explain the importance of and keep an accurate laboratory notebook. Given a case study, identify both scientific and societal ethical aspects. Explain cross-disciplinary concepts such as modularity, energy, modeling scientific phenomena, change over time and the differences between stochastic and deterministic phenomena Access and interpret safety information and conduct lab work safely and ethically. Give and take directions to be an effective team member.