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How does oxidative stress contribute to toxicology?

Topic

Pathways and transformations of energy and matter

Framing Question

How does oxidative stress contribute to toxicology?

Learning Objectives

  • Describe free radical forms of oxygen and nitrogen.
  • Describe the mechanism of lipid peroxidation.
  • Describe the defenses organisms have against free radicals.
  • Describe the nrf2 pathway and how it signals defense against oxidative stress.

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