Methods & Tools in Genetics
What experimental methods are commonly used to analyze gene structure and gene expression?
- Explain reverse genetics and compare methods for generating specific mutations in the genome vs. generating phenocopies using techniques such as RNAi or morpholinos.
- Explain the method of SNP/STR mapping and interpret SNP/STR mapping data to pinpoint the chromosomal location of a human disease gene.
- Interpret complementation tests, including an assessment of the molecular interactions that might yield the results observed.
- A Close-Up Look at PCR
- A Hands-on Introduction to Hidden Markov Models
- A Kinesthetic Modeling Activity to Teach PCR Fundamentals
- An Introduction to Eukaryotic Genome Analysis in Non-model Species for Undergraduates: A tutorial from the Genome Consortium for Active Teaching
- An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure
- Make It Stick: Teaching Gene Targeting with Ribbons and Fasteners
- Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience
- Predicting and classifying effects of insertion and deletion mutations on protein coding regions
- Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers
- The Case of the Missing Strawberries: RFLP analysis