DNA - Information Storage [GENOMICS]
Where are data about the genome found (e.g., nucleotide sequence, epigenomics) and how are they stored and accessed?
- Describe how nucleotide sequence data are represented (FASTA, FASTQ, GenBank).
- Describe the nucleotide databases available at NCBI.
- Describe how the NCBI nucleotide databases intersect with other nucleotide databases (EBI, DDBJ, UniProt, etc.).
- Compare and contrast the data contained in different nucleotide databases.
- Search for a sequence record in a nucleotide database with a given accession number.
- Create a collection of nucleotide sequence records that meet a specified criterion (e.g., gene name or symbol).
- Determine the DNA methylation state of a particular region of a genome.
- Describe the types of metadata that accompany sequence data to make for useful biological interpretation (e.g. biological source, accession number, GeneID, journal articles, etc.).
- A CRISPR/Cas Guide RNA Design In Silico Activity
- A CURE-based approach to teaching genomics using mitochondrial genomes
- A Hands-on Introduction to Hidden Markov Models
- An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure
- Exploration of the Human Genome by Investigation of Personalized SNPs
- Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience
- Predicting and classifying effects of insertion and deletion mutations on protein coding regions
- Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
- Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course
- Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans