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How can bioinformatics tools be employed to examine transfer of genetic information?

Topic

RNA - Information Transfer [TRANSCRIPTOMICS]

Framing Question

How can bioinformatics tools be employed to examine transfer of genetic information?

Learning Objectives

  • Given a microarray or RNA-seq data file, find the set of significantly differentially expressed genes.
  • Perform motif discovery on the promoter regions of a set of genes identified by a ChIP-seq experiment.
  • Use RNA structure prediction programs (e.g., RNASoft, RNAFold, RNAStructure) to evaluate possible structures for an RNA sequence.
  • Identify the possible different splice isoforms possible from a given gene sequence.

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